Robert Hedaya tried everything in mainstream psychiatry’s toolbox to treat a patient with panic disorder, including cognitive behavioral therapy and a series of prescribed medications. She was still having attacks after a year, though, so Hedaya went back to the lab to look at her case from a different perspective.
“Early in my training in psychiatry at Georgetown, I figured out that the way things look depends on the lens you use,” says Hedaya, MD, ABPN, DFAPA, founder of the National Center for Whole Psychiatry and clinical professor of psychiatry at Georgetown University School of Medicine. “If you use a low-powered lens to look at mental illness, you look at communities and culture. If you use a medium-powered lens, you look at family systems. If you use a high-powered lens, you look at molecules.”
He revisited the patient’s blood work and saw that her red cells were larger than normal. He did a literature search and found that a deficiency in B12 could be the cause, so he began a series of B12 injections. Within days, the panic attacks were over.
Now, Hedaya practices what he calls “whole psychiatry.” New patients undergo a four-hour workup, in which Hedaya examines all the factors that have combined to cause a break in a person’s mental health. Unlike his colleagues in mainstream psychiatry, he conducts extensive lab work to look for disruptions in basic body systems that might manifest as mental illness, while also looking into psychological, social, and spiritual factors.
“These are the same [disruptions] that underlie the chronic illnesses of Western society,” he explains. “Take inflammation, for instance: In one person, it might show up as diabetes, in another person as cardiovascular disease, in someone else as depression.”
Integrative psychiatrist and author Hyla Cass, MD, concurs. “Psychiatry is the only specialty that doesn’t test the organ involved, namely the brain,” she says. “If you have heart disease or hepatitis or diabetes, doctors will perform lab tests to monitor the system in question and treat accordingly. But if your inflamed brain shows symptoms of mental illness, all of a sudden they don’t consider the brain an organ anymore — they think we have to talk people out of that illness. Talk therapy and even the psychiatric medications can be helpful, but first we have to approach the biochemical root cause.”
Hedaya and Cass are part of a growing number of mental-health professionals who find the mainstream approach to mental illness insufficient. Many psychiatrists spend less than an hour evaluating a new patient and base their diagnosis and treatment plan on the symptoms that the patient reports and that they themselves see during the exam. Sometimes they will order scans to make sure a physical disorder — like a mass in the brain — isn’t causing the symptoms, but mostly they match the symptoms to a medication and, sometimes, recommend psychotherapy.
Integrative psychiatrists, on the other hand, might use these medications to stabilize a patient who is in a crisis state. Their overall goal, however, is to treat the underlying health issues through nutrition, supplementation, and lifestyle changes.
Treating the Whole Person
Curing patients with vitamins, as Hedaya did with the woman suffering panic attacks, is not new. In fact, this approach was the breakthrough treatment in mental health in the 1950s. Canadian physician and medical researcher Abram Hoffer began treating people with schizophrenia using niacin, or vitamin B3, and claimed a cure rate of 75 percent — meaning, he said, that these people were well enough to go back to work and pay taxes instead of needing to be supported by society. In 1968, Nobel Prize–winning scientist Linus Pauling — the great champion of megadose vitamin C — coined the term “orthomolecular,” which means “the right molecule,” to describe this method of treatment.
The ’50s also saw the introduction of the prescription drug Haldol and other such medications, and they were widely embraced by the medical profession over the years. But recently, there has been growing frustration with drug therapy among doctors as well as patients — the cure rate is abysmal and the side effects so vicious that even patients who feel better don’t want to continue the regimen.
According to Steven Carter, director of the International Society for Orthomolecular Medicine, those who advocate for high-dose vitamin treatments, as opposed to drug therapy, use nutrients that occur naturally in the body. And there are 40 essential nutrients that need to be balanced according to someone’s individual biochemistry.
“Medications can be quick,” says Jonathan Prousky, ND, MSc, editor of the Journal of Orthomolecular Medicine. “They will quickly subdue someone and make them docile, which makes people think they’re getting better. But they’re not getting better. I’ve never met a patient on an antipsychotic medication who was living a thriving, flourishing life. I’ve never seen it.”
There is a relative scarcity of research into the healing properties of vitamins and nutrition, because, frankly, there’s little profit to be made from these discoveries — unlike the money flowing from new FDA-approved drugs. Even worse, there is not enough awareness of the existing research, says Jeffrey Becker, MD, a Los Angeles psychiatrist and practitioner of functional medicine who specializes in schizophrenia.
Still, Becker and others are gathering this research and crafting multilayered treatment strategies that are proving effective even with schizophrenia, one of the most intractable and complex of mental illnesses. “With schizophrenia, it’s as if the dream world is penetrating your everyday consciousness,” he says. “All of us have the capacity to ‘hear voices’ — we do it in our dreams. In this disorder, it happens when it shouldn’t.”
Scientists believe that numerous genetic flaws create the propensity for schizophrenia, which may then be triggered by some form of stress, such as illness or extraordinary environmental pressures. In addition, people with schizophrenia and other mental illnesses often have lifestyles that compound the biochemical storm within. They frequently overuse stimulants and they smoke, which inactivates vitamin B6, depletes other nutrients, and increases oxidative stress. And they often have poor diets.
Integrative psychiatrists approach schizophrenia and other mental illness by treating the whole person, examining their problems through the different lenses that Hedaya describes. They urge them away from drugs, alcohol, and smoking; encourage exercise and a good night’s sleep; suggest healthy ways of connecting to other people, nature, and a spiritual practice; and combat biochemical imbalance with an array of supplements and other nutritional interventions (see next page for specific nutritional tips).
The good news is that when problems of the brain are treated with a whole-body approach, issues in other parts of the body often resolve. “Sometimes their skin clears up,” says naturopath Ray Pataracchia, ND. “Their energy level picks up. I had one client who said that everyone at work teased him because his abdomen looked like a basketball. When I treated him, his digestion improved and the ‘basketball’ went away.”
Not everyone seeking help for his or her own mental illness or that of a loved one can find a clinician committed to this whole-body treatment, but any committed clinician can learn the science behind these approaches. “All this is complicated, but it’s not rocket science,” says Becker. “It should be taught to psychiatrists, but it’s not. I had to learn it all on my own; most of the information is out there on PubMed.”
Patients and their families shouldn’t be shy about pushing their clinicians to look beyond the latest wonder drug and try to incorporate some orthomolecular strategies. “Patients should compel their doctors to prescribe vitamins,” says Andrew Saul. “Manage the doctor; don’t let the doctor manage you. It’s your body, your life, and the doctor works for you.”
Nutrition for Schizophrenia
What follows is a series of nutrition-based strategies integrative psychiatrists use to treat schizophrenia, one of the most perplexing of mental diagnoses.
Everyone requires a certain level of niacin, or vitamin B3, in his or her diet, but people with schizophrenia may not only be niacin deficient, they may be niacin dependent, meaning that they require a high dose — up to 3 grams or more daily — to function normally. Andrew Saul, PhD, editor in chief of the peer-reviewed Orthomolecular Medicine News Service, says that Canadian physician and medical researcher Abram Hoffer recommended pairing high doses of B3 with up to 10,000 milligrams of vitamin C, divided into smaller doses throughout the day to increase absorption. “Vitamin C is the body’s most important antioxidant,” Saul says. “Dr. Hoffer believed that, in addition to many other important properties, vitamin C prevented the oxidation of adrenaline to adrenochrome [which Hoffer believed could cause psychotic behavior].”
B6, B12, and folic acid